Clinical Research
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- Research done with XRHealth
Cognitive Behavioral Therapy (CBT) and (VR) Virtual Reality for Enhanced Therapeutic Outcomes: Exposure Therapy
Cognitive Behavioral Therapy, Prolonged Exposure Therapy, and EMDR in the Assessment and Treatment of PTSD using Virtual Reality
Justifying the Integration of Virtual Reality in Cognitive Behavioral Therapy: A Comprehensive Analysis of Return on Investment
The Applications of AI-Enhanced XR in Patient Diagnostics, Therapy, and Remote Monitoring
XRHealth Behavioral Space
XRHealth eXperience Space
Remotely conducted versus office-based virtual reality treatment for aviophobia: Questions of feasibility and accessibility. (2021).
Remotely conducted versus office-based virtual reality treatment for fear of flying. 52nd Annual Convention of the Association for Behavioral & Cognitive Therapies. (2018).
Virtual reality for management of pain in hospitalized patients: A randomized comparative effectiveness trial. (2019).
Effects of virtual reality on physical, cognitive, and psychological outcomes in cancer rehabilitation: A systematic review and meta-analysis. (2023).
An 8-week self-administered at-home behavioral skills-based virtual reality program for chronic low back pain: Double-blind, randomized, placebo-controlled trial conducted during COVID-19. (2021).
A data-centric artificial intelligent and extended reality technology in smart healthcare systems. (2022).
Exploring the Impact of Artificial Intelligence on Healthcare Management: A Combined Systematic Review and Machine- Learning Approach. (2024).
The combination of artificial intelligence and extended reality: A systematic review. (2021).
Aprendizaje automático y salud mental: de la promesa a la aplicación clínica. (2018).
Next-generation business models for artificial intelligence start-ups in the healthcare industry. (2021).
Internet-delivered cognitive behavioural therapy with and without an initial face-to-face psychoeducation session for social anxiety disorder: A pilot randomized controlled trial. (2015).
A study to investigate the effectiveness of the application of virtual reality technology in dental education. (2022).
Virtual reality for psycho-education on self-stigma in depression : Design of a randomised controlled trial. (2022).
Psychoeducational interventions in adolescent depression: A systematic review. (2018).
Chan, J. J. I., et al. (2020). The use of pre-operative virtual reality to reduce anxiety in women undergoing gynecological surgeries: A prospective cohort study. BMC Anesthesiology, 20(1), 261.
Immersive virtual reality on childbirth experience for women: A randomized controlled trial. (2022).
The use of virtual reality for peri-procedural pain and anxiety at an outpatient spine clinic injection visit: An exploratory controlled randomized trial. (2020).
Realidad virtual (RV) como estrategia de intervención innovadora: mindfulness mediante RV en niños con TDAH. (2017).
Developing, implementing and governing artificial intelligence in medicine: a step-by-step approach to prevent an artificial intelligence winter. (2022).
XR and AI: AI-enabled virtual, augmented, and mixed reality. (2023).
Herramientas de inteligencia artificial y soporte a la toma de decisiones en salud mental. (2022).
Psychoeducation on Stress and Anxiety Using Virtual Reality: A Mixed-Methods Study. (2022).
Psychological interventions for needle-related procedural pain and distress in children and adolescents. (2018).
Virtual reality as a distraction technique for pain and anxiety among patients with breast cancer: A randomized control trial. (2019).
The efficacy of virtual reality for persistent cancer pain: A call for research. (2019).
Virtual reality technology for pain and anxiety management among patients with cancer: A systematic review. (2020).
Efficacy of a mindfulness-based programme with and without virtual reality support to reduce stress in university students: A randomized controlled trial. (2021).
Effectiveness of virtual reality distraction interventions to reduce dental anxiety in paediatric patients: A systematic review and meta-analysis. (2023).
Promoting Emotional and Psychological Well-Being During COVID-19 Pandemic: A Self-Help Virtual Reality Intervention for University Students. (2023).
Effects of virtual reality-based relaxation techniques on psychological, physiological, and biochemical stress indicators. (2021).
COVID Feel Good—An Easy Self-Help Virtual Reality Protocol to Overcome the Psychological Burden of Coronavirus. (2020).
The efficacy of app-supported smartphone interventions for mental health problems: a meta-analysis of randomized controlled trials. (2019).
Evaluation of a VR system for Pain Management using binaural acoustic stimulation. (2019).
Impact of Virtual Reality (VR) experience on older adults’ well-being. (2018).
Virtual reality and stimulation of touch and smell for inducing relaxation: A randomized controlled trial. (2016).
Treatment of attention deficit hyperactivity disorder in children using mindfulness and VR. (2019).
Intensive care unit–specific virtual reality for critically ill patients with COVID-19: Multicenter randomized controlled trial. (2022).
Virtual reality for management of pain in hospitalized patients: A randomized comparative effectiveness trial. (2019).
How effective is virtual reality technology in palliative care? A systematic review and meta-analysis. (2022).
Virtual reality distraction induces hypoalgesia in patients with chronic low back pain: A randomized controlled trial. (2020).
Differential effects of two virtual reality interventions: Distraction versus pain control. (2014).
Use of virtual reality for the management of anxiety and pain in dental treatments: Systematic review and meta-analysis. (2020).
The impact of virtual reality on chronic pain. (2016).
Effects of virtual reality on physical, cognitive, and psychological outcomes in cancer rehabilitation: A systematic review and meta-analysis. (2023).
Innovative technology using virtual reality in the treatment of pain: Does it reduce pain via distraction, or is there more to it? (2018).
Garcia, L. M., et al. (2021). An 8-week self-administered at-home behavioral skills-based virtual reality program for chronic low back pain: Double-blind, randomized, placebo-controlled trial conducted during COVID-19. Journal of Medical Internet Research, 23(2), e26292.
Gao, Y., Wang, N., & Liu, N. (2023). Effectiveness of virtual reality in reducing preoperative anxiety in adults: A systematic review and meta-analysis. Journal of Advanced Nursing, 79(10), 3678–3690. https://doi.org/10.1111/jan.15743
Huguet-Miguel, A., Alda-Díez, J. A., Chamorro-Fernández M., Gelabert, J. M, & Insa-Pineda I. (2019, June). Mindfulness mediante realidad virtual en niños recientemente diagnosticados de TDAH vs programa de mindfulness estándar. Oral communication at 63º Congreso Nacional AEPNYA, Oviedo, Spain.
Sainz-Fuertes, R., Gelabert Mir, J., Valderas, J., Bullock, K., Giersch, A., Vogeley, K., & Maddox, T. (2020). COVID-19 and mental health: A review and the role of telehealth and virtual reality. Digital Medicine, 6(2), 53. https://doi.org/10.4103/digm.digm_22_20
Effect of a virtual reality exercise on patients undergoing haemodialysis: A randomised controlled clinical trial research protocol. (2023).
Virtual reality as an analgesic for acute and chronic pain in adults: A systematic review and meta-analysis. (2019).
Virtual reality and pain management: Current trends and future directions. (2011).
Virtual reality intervention for patients with neck pain: A systematic review and meta-analysis of randomized controlled trials. (2022).
Feasibility of delivering an avatar-facilitated life review intervention for patients with cancer. (2021).
Virtual reality for management of pain in hospitalized patients: Results of a controlled trial. (2017).
Virtual reality as a clinical tool for pain management. (2018).
Keshner, E. A., Keshner, E. A., & Kenyon, R. V. (2004). Using Immersive Technology for Postural Research and Rehabilitation. Assistive Technology, 16(1), 54–62. https://doi.org/10.1080/10400435.2004.10132074
Gumaa, M., & Rehan Youssef, A. (2019). Is Virtual Reality Effective in Orthopedic Rehabilitation? A Systematic Review and Meta-Analysis. Physical Therapy, 99(10), 1304–1325. https://doi.org/10.1093/ptj/pzz093
Gavish, L., Weissberger, O., & Barzilay, Y. (2023). Gamification of Cervical Spine Physiotherapy by Virtual Reality Software: Is This Real Rehabilitation? Games for Health Journal, 12(6), 468–471. https://doi.org/10.1089/g4h.2023.0036
Domínguez-Téllez, P., Moral-Muñoz, J. A., Salazar, A., Casado-Fernández, E., & Lucena-Antón, D. (2020). Game-Based Virtual Reality Interventions to Improve Upper Limb Motor Function and Quality of Life After Stroke: Systematic Review and Meta-analysis. Games for Health Journal, 9(1), 1–10. https://doi.org/10.1089/g4h.2019.0043
Reliability Comparisons of Cervical Active Range of Motion Measuring Methods: Universal Goniometer versus Virtual Reality. (2022).
Reliability Comparisons of Cervical Active Range of Motion Measuring Methods: Universal Goniometer versus Virtual Reality. (2022).
Immersive Virtual Reality as a Novel Physical Therapy Approach for Nonagenarians: Usability and Effects on Balance Outcomes of a Game-Based Exercise Program. (2022).
Aplicación De Un Programa De Realidad Virtual Como Herramienta De Reducción De La Ansiedad Anticipatoria a Una Sesión De Quimioterapia. (2022).
Feasibility and patient satisfaction of the use of virtual reality during office hysteroscopy. (2021).
Prueba piloto de aplicación de la realidad virtual para el manejo del dolor y la ansiedad anticipatoria en pacientes de hemodiálisis. (2021).
Virtual reality as an adjunct to anesthesia in the operating room. (2019).
The effects of virtual reality‐based exercise in adults receiving haemodialysis treatment: A systematic review and meta‐analysis of randomized controlled studies. (2022).
Effectiveness of virtual reality in symptom management of cancer patients: A systematic review and meta-analysis. (2023).
Virtual reality as a distraction technique in chronic pain patients. (2014).
Virtual reality (VR) to reduce anxiety in children in the plaster room: A study protocol for a randomized controlled trial. (2022).
A novel palliative care approach using virtual reality for improving various symptoms of terminal cancer patients: A preliminary prospective, multicenter study. (2019).
Virtual Reality Combined with Artificial Intelligence (VR-AI) Reduces Hot Flashes and Improves Psychological Well-Being in Women with Breast and Ovarian Cancer: A Pilot Study. (2022).
Effectiveness of virtual reality on activities of daily living after stroke: A systematic review. (2022).
The effect of virtual reality program on the cognitive function and balance of the people with mild cognitive impairment. (2017).
Virtual Reality and Medical Inpatients: A Systematic Review of Randomized, Controlled Trials. (2017).
Use of immersive virtual reality to assess episodic memory: A validation study in older adults. (2020).
Balancing new technology: Virtual reality for balance measurement case report. (2023).
Eight-week virtual reality training improves lower extremity muscle strength but not balance in adolescents with intellectual disability: A randomized controlled trial. (2022).
Virtual reality-based physical therapy for patients with lower extremity injuries: feasibility and acceptability. (2021).
Effects of virtual reality-based planar motion exercises on upper extremity function, range of motion, and health-related quality of life: a multicenter, single-blinded, randomized, controlled pilot study. (2019).
Using Virtual Reality to Transfer Motor Skill Knowledge from One Hand to Another. (2017).
Virtual reality in the management of patients with low back and neck pain: a retrospective analysis of 82 people treated solely in the metaverse. (2023).
Nekar, D. M., Kang, H. Y., & Yu, J. H. (2022). Improvements of Physical Activity Performance and Motivation in Adult Men through Augmented Reality Approach: A Randomized Controlled Trial. Journal of Environmental and Public Health, 2022. https://doi.org/10.1155/2022/3050424
Miller, K. J., Adair, B. S., Pearce, A. J., Said, C. M., Ozanne, E., & Morris, M. M. (2014). Effectiveness and feasibility of virtual reality and gaming system use at home by older adults for enabling physical activity to improve health-related domains: A systematic review. Age and Ageing, 43(2), 188–195. https://doi.org/10.1093/ageing/aft194
Levin, M. F., et al. (2015). Emergence of virtual reality as a tool for upper limb rehabilitation: incorporation of motor control and motor learning principles. Physical Therapy, 95(3), 415-425.
Lee, H. S., Park, Y. J., & Park, S. W. (2019). The effects of virtual reality training on function in chronic stroke patients: A systematic review and meta-analysis. BioMed Research International, 2019. https://doi.org/10.1155/2019/7595639
Cano-Mañas, M. J., et al. (2020). Effects of Video-Game Based Therapy on Balance, Postural Control, Functionality, and Quality of Life of Patients with Subacute Stroke: A Randomized Controlled Trial. Journal of Healthcare Engineering, 2020, 1-11.
Asadzadeh, A., Samad-Soltani, T., Salahzadeh, Z., & Rezaei-Hachesu, P. (2021). Effectiveness of virtual reality-based exercise therapy in rehabilitation: A scoping review. Informatics in Medicine Unlocked, 24, 100562. https://doi.org/10.1016/j.imu.2021.100562
Adomavičienė, A., Daunoravičienė, K., Kubilius, R., Varžaitytė, L., & Raistenskis, J. (2019). Influence of New Technologies on Post-Stroke Rehabilitation: A Comparison of Armeo Spring to the Kinect System. Medicina, 55(4), 98. https://doi.org/10.3390/medicina55040098
Differentiation of mild cognitive impairment using an entorhinal cortex-based test of virtual reality navigation. (2019).
Immersive Virtual Reality in Cognitive Rehabilitation: A systematic Review. (2022).
Virtual Reality in Stroke Rehabilitation. (2011).
Comparison of virtual reality rehabilitation and conventional rehabilitation in Parkinson’s disease: a randomised controlled trial. (2020).
Neuroscience of Virtual Reality: From Virtual Exposure to Embodied Medicine. (2019).
A Systematic Literature Review of Virtual Reality-based Reminiscence Therapy for People with Cognitive Impairment or Dementia. (2022).
Psychological and Physiological Responses in Patients with Generalized Anxiety Disorder: The Use of Acute Exercise and Virtual Reality Environment. (2020).
The Effectiveness of Virtual Reality Exposure–Based Cognitive Behavioral Therapy for Severe Anxiety Disorders, Obsessive-Compulsive Disorder, and Posttraumatic Stress Disorder: Meta-analysis. (2022).
Technologically-enhanced psychological interventions for older adults: a scoping review. (2020).
Virtual Reality Exposure Therapy Compared to Prolonged Exposure Therapy With and Without D-Cycloserine. (2023).
Virtual reality relaxation for people with mental health conditions: a systematic review. (2023).
Emerging Utility of Virtual Reality as a Multidisciplinary Tool in Clinical Medicine. (2017).
Virtual reality interventions for victims of crime: A systematic review. (2022).
The Role of Virtual Reality in Cancer Pain Management: A Systematic Literature Review. (2023).
Virtual Reality Applications in Chronic Pain Management: Systematic Review and Meta-analysis. (2022).
Virtual reality technology in neuropsychological testing: A systematic review. (2023).
Virtual reality and augmented reality as strategies for teaching social skills to individuals with intellectual disability: A systematic review. (2022).
Feasibility and usability of a non-immersive virtual reality tele-cognitive app in cognitive rehabilitation of patients affected by Parkinson’s disease. (2022).
Liu, Q., Song, H., Yan, M., Ding, Y., Wang, Y., Chen, L., & Yin, H. (2023). Virtual reality technology in the detection of mild cognitive impairment: A systematic review and meta-analysis. Ageing Research Reviews, 87(September 2022), 101889. https://doi.org/10.1016/j.arr.2023.101889
Ho, K. Y., Cheung, P. M., Cheng, T. W., Suen, W. Y., Ho, H. Y., & Cheung, D. S. K. (2022). Virtual Reality Intervention for Managing Apathy in People with Cognitive Impairment: Systematic Review. JMIR Aging, 5(2). https://doi.org/10.2196/35224
Hali, K., Manzo, M. A., Koucheki, R., Wunder, J. S., Jenkinson, R. J., Mayo, A. L., … Lex, J. R. (2023). Use of virtual reality for the management of phantom limb pain: a systematic review. Disability and Rehabilitation, 1–8. https://doi.org/10.1080/09638288.2023.2172222
Kalron, A., Frid, L., Fonkatz, I., Menascu, S., Dolev, M., Magalashvili, D., & Achiron, A. (2022). The Design, Development, and Testing of a Virtual Reality Device for Upper Limb Training in People With Multiple Sclerosis: Single-Center Feasibility Study. JMIR Serious Games, 10(3), 1–8. https://doi.org/10.2196/36288
Virtual reality interventions for the treatment of anxiety disorders: A scoping review. (2023).
Highlighting hybridization: a case report of virtual reality-augmented interventions to improve chronic post-stroke recovery. (2022).